This workshop reveals how pioneering microfluidic technology enables the precise manipulation of physiologically relevant micro-environments, helping researchers connect cellular mechanisms and phenotypes with disease states. We will discuss the techniques of using microfluidic cell culture tools to develop and quantify in vitro cell models for predictive cell analysis. Researchers will gain insight into the utility of a flexible microfluidic cell culture workflow combined with current live cell imaging technologies. Applications that will be covered include drug dose/response, 3D live cell imaging, cell migration in a chemo-spatial gradient, gene expression dynamics, stem cell/primary cell culture, and more.
Microfluidic cell culture chambers allow crucial parameters such as media feeding, temperature and gas environment to be automated on any inverted microscope. This enables researchers to recreate the mass transport environment of tissues, elicit cell responses to dynamic solution changes and enable long-term perfusion culture during long-term live cell imaging. A demonstration of the CellASIC™ ONIX Platform will follow the talk and individual appointment slots may be reserved for researchers who wish to have a closerlook at the system during the meeting.
